Friday, January 8, 2010

How will Cyanide affect the H+ gradient? How will it affect the production of ATP?

(Cyanide is a poison that prevents the transfer of electrons from the electron carriers to oxygen)How will Cyanide affect the H+ gradient? How will it affect the production of ATP?
Cyanide 鈥?cyanide will inhibit the electron transport chain, preventing


electrons from reaching O2 and preventing protons from being pumped out,


thus preventing ATP synthesis. If electrons can鈥檛 be disposed of, then


NADH will not be reoxidized and glycolysis will initially be inhibited, unless


it can carry out fermentation to meet its energy needs. Then glucose


breakdown will increase to supply those needs with a less efficient pathway.

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